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A 37-year-old bull African elephant (Loxodonta africana) at the North Carolina Zoo (NCZ) was diagnosed with bilateral cataracts leading to behavioral changes and significant weight loss secondary to functional blindness.On initial examination, a weight loss of 234 kg, a mature cataract in the right eye, and a focal cataract in the left eye were dia
Non-small cell lung carcinoma (NSCLC) is the leading cause of cancer-related deaths globally.Immune checkpoint blockade (ICB) has transformed cancer medicine, with anti-programmed cell death protein 1 (anti-PD-1) therapy now well-utilized for treating NSCLC.Still, not all patients with NSCLC respond positively to anti-PD-1 therapy, and some patient
Thirteen new lethal cases of acute hemorrhagic disease (HD) with typical histopathogical features were identified in young Asian elephants (Elephas maximus indicus) in India between 2013 and 2017.Eight occurred amongst free-ranging wild herds, with three more in camp-raised orphans and two in captive-born calves.All were confirmed to have high leve
The shipbuilding design rules require several criteria for the assessment of any floating structure.For this technical paper, a 23000 t off-shore barge is assessed by oblique waves global strength criteria.Two barge concepts are evaluated, with the main changes of breadth and draught.Focusing on the gemplers coupon preliminary analysis that involve